Brimstone

Variational Inverse Planning

Brimstone (formerly released as pheonixrt) is an embodiment of our variational inverse planning algorithm. It utilizes the physician’s intent dose targets as a prior, and estimates the posterior (actual) DVH using a gradient-friendly approximation. The commonly used Kullback-Liebler divergence provides a robust means of performing the estimation.

Toward Compositional Energy-Based Models

We are currently exploring ways that the variational objective can be used as part of a compositional energy-based model, which can provide a powerful means of combining multiple knowledge sources to guide synthesis in an appropriate latent space.